Dr. Christopher S. Kovacs - Endocrinologist  
     
     
Education
1989 MD Queen's University at Kingston, Ontario, Canada
1991 BA Queen's University at Kingston, Ontario, Canada

Post Doctoral Training
1989-90 Intern, Comprehensive Medicine
Queen's University at Kingston, Ontario, Canada
1990-91 Junior Resident, Internal Medicine
Queen's University at Kingston, Ontario, Canada
1991-92 Senior Resident, Internal Medicine
Queen's University at Kingston, Ontario, Canada
1992-94 Endocrinology and Metabolism Subspecialty Training Resident
University of Alberta, Edmonton, Alberta, Canada

Research Fellowships
1994-97 Post-Doctoral Research Fellow in Bone and Mineral Metabolism
Massachusetts General Hospital / Harvard Medical School, Boston, MA, USA
2008 Training in bone histomorphometry, St. Vincent's Institute, University of Melbourne, Australia

Licensure and Board Certification
BOARD CERTIFICATION
1990 Licentiate of the Medical Council of Canada
1993 Fellow of the Royal College of Physicians and Surgeons of Canada
1993 Specialist Certificate in Internal Medicine,
Royal College of Physicians and Surgeons of Canada
1994 Certificate of Special Competence in Endocrinology and Metabolism,
Royal College of Physicians and Surgeons of Canada
1999 Fellow of the American College of Physicians
2011 Fellow of the American College of Endocrinology

MEDICAL LICENSURE
1990-99 College of Physicians and Surgeons of Ontario
1997- Commonwealth of Massachusetts, Unrestricted License
1997- Newfoundland Medical Board, General License

Academic & Administrative Appointments
Professor of Medicine (Endocrinology), Obstetrics & Gynecology and BioMedical Sciences , Memorial University of Newfoundland

Hospital Appointments
Attending Physician (Endocrinology and Internal Medicine), General Hospital, Health Sciences Centre
Consultant Physician in Endocrinology and Metabolism, Leonard A Miller Centre, St. Clare's Hospital, Waterford Hospital

Memberships, Offices and Committee Appointments
Canadian Medical Association
American College of Physicians
Canadian Medical Protective Association
Royal College of Physicians and Surgeons of Canada - Gold Medal Award Committee
The Endocrine Society
Canadian Society of Endocrinology and Metabolism - Council Member
American Society for Bone and Mineral Research
American Association for the Advancement of Science
Massachusetts Medical Society
American Medical Association
Newfoundland and Labrador Medical Association
International Bone and Mineral Society
Atlantic Endocrine Society
American Association of Clinical Endocrinologists
Canadian Society of Clinical Investigation - Council Member; Membership Committee; Award Committee
Advances in Mineral Metabolism - Board Member, Vice President, President

Institute of Medicine, National Academies of Science, USA: 2008-2010 Committee on Dietary Reference Intakes for Calcium and Vitamin D

Other Professional Positions & Major Appointments
1994-97 Research Fellow in Medicine, Harvard Medical School
1997-01 Assistant Professor of Medicine (Endocrinology), Obstetrics & Gynecology and Basic Medical Sciences, Memorial University of Newfoundland
2001-04 Associate Professor of Medicine (Endocrinology), Obstetrics & Gynecology and Basic Medical Sciences Memorial University of Newfoundland

Awards & Honors

1994-98 Medical Research Council of Canada Fellowship Award
1994 University of Alberta Residents' Research Day Award
1995 Young Investigator Award
American Society for Bone and Mineral Research
1996 10th International Congress of Endocrinology / Endocrine Society Travel Award
1997 NIH Research Award / Keystone Symposium on Molecular Biology
1998 Endocrine Society Travel Award
1998 D. Harold Copp Award Young Investigator Award / Canadian Society for Endocrinology and Metabolism
1999 John C. Haddad Young Investigator Award from the American Society for Bone and Mineral Research and the Society for Advances in Mineral Metabolism
1999-04 Scholarship from Medical Research Council of Canada
1999 Elected to Fellowship in the American College of Physicians
2000 Program Committee, 22nd American Society for Bone and Mineral Research
2001 Early promotion and tenure, Memorial University of Newfoundland
2002 President's Award for Outstanding Research, Memorial University
2002 Antoni Nalecz Award, Canadian Society of Endocrinology and Metabolism
2003 Gold Medal in Medicine, Royal College of Physicians and Surgeons of Canada
2003-13 Program Committee, Annual Meetings of the American Society for Bone and Mineral Research
2003 Young Investigator Award, Canadian Society of Endocrinology and Metabolism
2003 Ad Hoc Member, Endocrinology Committee, Canadian Institutes of Health Research
2003-present Council Member, Canadian Society of Endocrinology and Metabolism
2003-12 Council Member, Canadian Society for Clinical Investigation
2004-07 Educational Committee, American Society for Bone and Mineral Research
2004-09 Charter Member, Study Section on Skeletal Development Biology and Disease, National Institutes of Health (NIH)
2005-present Canadian Who's Who
2006 Chair and Host of the 9th International Conference on PTH and PTHrP (AKA The Newfoundland Bone Conference)
2006-10 Gold Medal Award Committee, Royal College of Physicians and Surgeons of Canada
2007-10 Board Member, Advances in Mineral Metabolism
2008-11 Publications Committee, American Society for Bone and Mineral Research
2008 Painting "Green Gables House" selected by Canada Post and Japan Post for a stamp issued jointly by both countries in June 2008
2009-10 Committee on Dietary Reference Intakes of Calcium and Vitamin D, Institute of Medicine, National Academies of Science, USA
2011  Fellow, American College of Endocrinology
2012 Anast Lecture, Brigham and Women’s Hospital, Boston Children’s Hospital, Harvard Medical School
2013-15  Vice President, Advances in Mineral Metabolism
2015-17 President, Advances in Mineral Metabolism

 


Editorial Boards

Editorial Boards:
2004-14 Journal of Bone and Mineral Research
2004-07 Royal College Outlook
2009-12 Endocrinology

2014-17 Endocrinology


Peer Reviewer for these journals:
Endocrinology
Journal of Bone and Mineral Research
Bone
Molecular and Cellular Endocrinology
Journal of Clinical Endocrinology and Metabolism
Molecular Endocrinology
American Journal of Physiology
Placenta
Canadian Journal of Physiology and Pharmacology
Pediatrics
Journal of Human Lactation
among others

Peer Reviewer for the following grant agencies and societies:
Annual Meetings of the Endocrine Society;
American Society for Bone and Mineral Research; Canadian Diabetes Association/Canadian Society of Endocrinology and Metabolism
Burroughs Wellcome Trust Foundation (UK)
Canadian Institutes of Health Research
Hospital for Sick Children Foundation, National Grants Program Committee
Dairy Farmers of Canada Grants and Awards
Science Foundation Ireland
National Institutes of Health, Study Section on Skeletal Biology Development and Diseases


Research Interests
Basic Research Projects

The research in the lab of Dr. Kovacs is focused on the regulation of calcium and bone metabolism during the reproductive periods, including pregnancy, lactation, and fetal development. Mammalian fetuses regulate calcium and bone metabolism in a manner distinct from adults, reflecting the unique needs of the developing fetus (e.g. mineralization of skeleton, active transfer of calcium across the placenta) and the developmental roles of certain hormones (e.g. parathyroid hormone-related protein or PTHrP). Little is known about how the fetus accomplishes this regulation, or how and when the normal adult regulatory mechanisms are established after birth. During pregnancy and especially during lactation, calcium and other minerals are borrowed from the mother's skeleton to provide to the fetus or the milk, and then the lost calcium is restored to the mother's skeleton without any permanent loss in bone strength or density. It is particularly important to determine how the mother's skeleton is able to regain bone mass so quickly and readily, because the adult skeleton is normally unable to gain bone mass that has been lost. The mother's skeleton regains bone mass after weaning at a rate that exceeds the efficacy of our current pharmacological treatments for osteoporosis.

The research largely utilizes specific transgenic and gene knockout mouse models, molecular techniques, radiological techniques (including bone mineral density by DXA on small animals), and classical physiological studies, to focus on several areas:

1) Hormonal regulation of active placental calcium and phosphorus transfer and fetal mineral homeostasis;

2) Molecular mechanism(s) of calcium and phosphorus transfer at the level of the trophoblasts and intraplacental yolk sac cells;

3) Neonatal transition from fetal to adult regulatory mechanisms for mineral homeostasis;

4) Regulation of mineral and bone homeostasis during pregnancy and lactation.

Further information about research in Dr. Kovacs's lab can be obtained by clicking here.

Clinical Research Projects

Participating as an Investigator in several multi-centre clinical pharmaceutical trials of therapies for osteoporosis and diabetes.

Bibliography
Partial list of Peer-Reviewed Journal Articles and Research Papers

11. Kovacs CS, Chik CL. Hyperprolactinemia caused by lactation and prolactinomas is associated with altered serum calcium, phosphate, parathyroid hormone (PTH) and PTH-related peptide levels. Journal of Clinical Endocrinology and Metabolism 1995; 80(10):3036-3042.

13. Kovacs CS, Lanske B, Hunzelman JL, Guo J, Karaplis AC, Kronenberg HM. Parathyroid hormone-related peptide (PTHrP) regulates fetal-placental calcium transport through a receptor distinct from the PTH/PTHrP receptor. Proceedings of the National Academy of Sciences USA 1996; 93(26):15233-15238.

14. Kovacs CS, Kronenberg HM. Maternal-fetal calcium and bone metabolism during pregnancy, puerperium and lactation. Endocrine Reviews 1997; 18(6): 832-872.

15. Schipani E, Lanske B, Hunzelman J, Luz A, Kovacs CS, Lee K, Pirro A, Kronenberg HM, Jüppner H. Targeted expression of constitutively active PTH/PTHrP receptors delays endochondral bone formation and rescues PTHrP-less mice. Proceedings of the National Academy of Sciences USA 1997;94(25):13689-13694.

16. Kovacs CS, Ho-Pao C, Hunzelman JL, Lanske B, Fox J, Seidman JG, Seidman CE, Kronenberg HM. Regulation of murine fetal-placental calcium metabolism by the calcium sensing receptor. Journal of Clinical Investigation. 1998;101(12):2812-2820.

17. Lanske B, Divieti P, Kovacs CS, Pirro A, Landis WJ, Krane SM, Bringhurst FR, Kronenberg HM. The parathyroid hormone/parathyroid hormone-related peptide receptor mediates actions of both ligands in murine bone. Endocrinology 1998;139(12):5194-5204.

20. Kovacs CS, Manley NR, Moseley JM, Martin TJ, Kronenberg HM. Fetal parathyroids are not required to maintain placental calcium transport. Journal of Clinical Investigation 2001;107(8):1007-1015.

21. Kovacs CS. Calcium and bone metabolism in pregnancy and lactation. Journal of Clinical Endocrinology and Metabolism 2001; 86(6): 2344-2348.

22. Kovacs CS, Chafe LL, Fudge NJ, Friel JK, Manley NR. PTH regulates fetal blood calcium and skeletal mineralization independently of PTHrP. Endocrinology 2001; 142(11): 4983-4993.

23. Kovacs CS, Chafe LL, Woodland ML, McDonald KR, Fudge NJ, Wookey PJ. Calcitropic gene expression in the murine placenta suggests a role for the intraplacental yolk sac in maternal-fetal calcium exchange. American Journal of Physiology - Endocrinology and Metabolism 2002; 282(3): E721-E732.

25. Brasier G, Tikellis C, Xuereb L, Craigie J, Casley D, Kovacs CS, Fudge NJ, Kalnins R, Cooper ME, Wookey PJ. Novel hexad repeats conserved in a putative transporter with restricted expression in cell types associated with growth, calcium exchange and homeostasis. Experimental Cell Research 2004; 293:31-42.

26. Rubin LP, Kovacs CS, Pinar H, Tsai SW, Torday JS, Kronenberg HM. Arrested pulmonary alveolar cytodifferentiation and defective surfactant synthesis in mice missing the gene for parathyroid hormone-related protein. Developmental Dynamics 2004; 230: 278-289.

27. Fudge NJ, Kovacs CS. Physiological studies in heterozygous calcium sensing receptor (CaSR) gene-ablated mice confirm that the CaSR regulates calcitonin release in vivo. BMC Physiology 2004; 4:5.

28. McDonald KR, Fudge NJ, Woodrow JP, Friel JK, Hoff AO, Gagel RF, Kovacs CS. Ablation of calcitonin/calcitonin gene related peptide impairs fetal magnesium but not calcium homeostasis. American Journal of Physiology - Endocrinology and Metabolism 2004; 287: E218-E226.

29. Kovacs CS, Woodland ML, Fudge NJ, Friel JK. The vitamin D receptor is not required for fetal mineral homeostasis or for the regulation of placental calcium transfer in mice. American Journal of Physiology - Endocrinology and Metabolism 2005; 289(1):E133-44.

30. Kovacs CS. Calcium and bone metabolism during pregnancy and lactation. Journal of Mammary Gland Biology and Neoplasia 2005; 10(2):105-118.

31. Kovacs CS, El-Hajj Fuleihan G. Calcium and bone disorders during pregnancy and lactation. Endocrinology and Metabolism Clinics of North America 2006; 35(1); 21-51.

32. Woodrow JP, Sharpe CJ, Fudge NJ, Hoff AO, Gagel RF, Kovacs CS. Calcitonin plays a critical role in regulating skeletal mineral metabolism during lactation in mice. Endocrinology 2006; 147(9):4010-21.

34. Suzuki Y, Kovacs CS, Takanaga H, Peng JB, Landowski CP, Hediger MA. The calcium channel TRPV6 is involved in murine maternal-fetal calcium transport. Journal of Bone and Mineral Research 2008; 23(8):1249-56.

35. Kovacs CS. Vitamin D in pregnancy and lactation: maternal, fetal and neonatal outcomes from clinical and animal studies. American Journal of Clinical Nutrition 2008;88(Suppl):520S-528S.

36. Langsetmo L, Hanley DA, Kreiger N, Jamal SA, Prior J, Adachi JD, Davison KS, Kovacs CS, Anastassiades T, Tenenhouse A, Goltzman D; CaMos Research Group. Geographic variation of bone mineral density and selected risk factors for prediction of incident fracture among Canadians 50 and older. Bone 2008 Oct;43(4):672-8

 

40. Simmonds CS, Karsenty G, Karaplis AC, Kovacs CS.  Parathyroid hormone regulates fetal-placental mineral homeostasis. Journal of Bone and Mineral Research 2010; 25(3): 594-605. Epub 31 August 2009.

 

41. Fudge NJ, Kovacs CS. Pregnancy upregulates intestinal calcium absorption and skeletal mineralization independently of the vitamin D receptor. Endocrinology 2010; 151(3): 886-95. Epub 10 Jan 2010.

 

42. Langsetmo L, Morin S, Kovacs CS, Kreiger N, Josse R, Adachi JD, Papaioannou A, Goltzman D, Hanley DA, Olszynski WP, Prior J, Jamal SA, and the CaMos Research Group. Determining whether women with osteopenic BMD have low, moderate, or high clinical fracture Risk. Menopause 2010; Sep-Oct;17(5):1010-6.

 

43. Langsetmo L, Leslie WD, Zhou W, Goltzman D, Kovacs CS, Prior J, Josse R, Olszynski WP, Davison S, Anastassiades T, Towheed T, Hanley DA, Kaiser S, Kreiger N and the CaMos Group. Using the same bone density reference database for men and women provides a simpler estimation of fracture risk. Journal of Bone and Mineral Research 2010; 25(10): 2108-2114. Epub 30 April 2010.

 

44. Leslie WD, Berger C, Langsetmo L, Lix LM, Adachi JD, Hanley DA, Ioannidis G, Josse RG, Kovacs CS, Towheed T, Kaiser S, Olszynski WP, Prior JC, Jamal S, Kreiger N, Goltzman D; Canadian Multicentre Osteoporosis Study (CaMos) Research Group. Construction and validation of a simplified fracture risk assessment tool for Canadian women and men: results from the CaMos and Manitoba cohorts. Osteoporosis International 2010; in press. Epub 22 October 2010.

 

45. Ross AC, Manson JE, Abrams SA, Aloia JF, Brannon PM, Clinton SK, Durazo-Arvizu RA, Gallagher JC, Gallo RL, Jones G, Kovacs CS, Mayne ST, Rosen CJ, Shapses SA. The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: What clinicians need to know. Journal of Clinical Endocrinology and Metabolism 2011; 96(1): 53-58. Epub 29 November 2010.

 

46. Fraser LA, Langsetmo L,Berger C, Ioannidis G, Goltzman D, Adachi JD, Papaioannou A, Josse R, Kovacs CS, Olszynski WP, Towheed T, Hanley DA, Kaiser SM,  Prior J, Jamal S, Kreiger N, Brown J,  Johansson H, Oden A, McCloskey E, Kanis JA, Leslie WD and the CaMos Research Group. Fracture Prediction and Calibration of a Canadian Frax® Tool: a Population-Based Report from Camos. Osteoporosis International 2011; 22(3): 829-37. Epub 16 December 2010.

 

47.  Simmonds CS and Kovacs CS. The role of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in regulating mineral homeostasis during fetal development. Critical Reviews in Eukaryotic Gene Expression 2010; 20(3): 235-273.

 

48. Langsetmo L, Nguyen TV, Nguyen D, Kovacs CS, Prior JC, Morin S, Robert G Josse RG, Adachi JD, Hanley DA, Eisman JA. Independent external validation of nomograms for low trauma fracture and hip fracture risk in a population of Canadian men and women ages 55-95. Canadian Medical Association Journal 2011; 183(2): E107-E114. Epub 20 Dec 2010.

 

49. Liu Z, Farley A, Chen L, Kirby BJ, Kovacs CS, Blackburn CC, Manley NR. Thymus-associated parathyroid hormone has two cellular origins with distinct endocrine and immunological functions. PLoS Genetics 2010; 6(12):e1001251. Epub 23 Dec 2010.

 

50. Kirby BJ, Ardeshirpour L, Woodrow JP, Wysolmerski JJ, Sims NA, Karaplis AC, Kovacs CS. Skeletal recovery after lactation does not require PTHrP. Journal of Bone and Mineral Research 2011; in press. Epub 1 Feb 2011.

 

51. Ross AC, Manson JE, Abrams SA, Aloia JF, Brannon PM, Clinton SK, Durazo-Arvizu RA, Gallagher JC, Gallo RL, Jones G, Kovacs CS, Mayne ST, Rosen CJ, Shapses SA. The 2011 dietary reference intakes for calcium and vitamin D: What dietetic practitioners need to know. J Am Diet Assoc 2011;111(4):524-7.

 

52. Leslie WD, Kovacs CS, Olszynski WP, Towheed T, Kaiser SM, Prior JC, Josse RG, Jamal SA, Kreiger N, Goltzman D, and the CaMos Research Group. Spine-hip T-score difference predicts major osteoporotic fracture risk independent of FRAX®: a population-based report from CaMOS. Journal of Clinical Densitometry 2011; Jul-Sep;14(3):286-93. Epub 30 Jun 2011.

 

53. Kovacs CS. Bone development in the fetus and neonate: role of the calciotropic hormones. Current Osteoporosis Reports 2011; 9: 274-83. Epub 9 Sep 2011.

 

55. Kovacs CS. Calcium and bone disorders during pregnancy and lactation.  Endocrinology and Metabolism Clinics of North America 2011; 40: 795–826.

 

56. Berger C, Greene-Finestone LS, Langsetmo L, Kreiger N, Joseph L, Kovacs CS, Richards JB, Hidiroglou N, Sarafin K, Davison KS, Adachi JD, Brown J, Hanley DA, Prior JC, Goltzman D and the CaMos Research Group. Temporal trends and determinants of longitudinal change in 25-Hydroxyvitamin D and parathyroid hormone levels. Journal of Bone and Mineral Research 2012; 27(6):1381-1389. Epub 9 Mar 2012.

 

57. Rosen CJ, Abrams SA, Aloia JF, Brannon PM, Clinton SK, Durazo-Arvizu RA, Gallagher JC, Gallo RL, Jones G, Kovacs CS, Manson JE, Mayne ST, Ross AC, Shapses SA, Taylor CL. IOM committee members respond to Endocrine Society Vitamin D Guideline. Journal of Clinical Endocrinology and Metabolism 2012; 97(4):1146-52. Epub 22 Mar 2012.

 

58. Kovacs CS. The role of vitamin D in pregnancy and lactation: Insights from animal models and clinical studies. Annual Review of Nutrition. 2012; 32: 97-123. Epub 5 Apr 2012.

 

59. Rosen CJ, Adams JS, Bikle DB, Black DM, Demay MB, Manson JE, Murad MH, Kovacs CS. The Nonskeletal Effects of Vitamin D: an Endocrine Society Scientific Statement. Endocrine Reviews 2012; 33(3): 456-492. Epub 17 May 2012.
 

 

61. Koller DL, Zheng HF, Karasik D, Yerges-Armstrong L, Liu CT, McGuigan F, Kemp JP, Giroux S, Lai D, Edenberg HJ, Peacock M, Czerwinski SA, Choh AC, McMahon G, St Pourcain B, Timpson NJ, Lawlor DA, Evans DM, Towne B, Blangero J, Carless MA, Kammerer C, Goltzman D, Kovacs CS, Prior JC, Spector TD, Rousseau F, Tobias JH, Akesson K, Econs MJ, Mitchell BD, Richards JB, Kiel DP, Foroud T. Meta-Analysis of Genome-Wide Studies Identifies Wnt16 And Esr1 Snps Associated With Bone Mineral Density In Premenopausal Women. Journal of Bone and Mineral Research 2013; 28(3): 547-58. Epub 16 Oct 2012.

 

62. Kovacs CS. Maternal vitamin D deficiency: fetal and neonatal implications. Seminars in Fetal & Neonatal Medicine 2013; 18(3): 129-135. Epub 13 Feb 2013.  

 

63. Collins JN, Kirby BJ, Woodrow JP, Gagel RF, Rosen CJ, Sims NA, Kovacs CS. Lactating Ctcgrp nulls lose twice normal bone mineral content due to fewer osteoblasts and more osteoclasts, while bone mass is fully restored post-weaning in association with upregulation of Wnt signaling and other novel genes. Endocrinology 2013; 154(4): 1400-1413. Epub 5 Mar 2013.

 

64. Kirby BJ, Ma Y, Martin HM, Buckle Favaro KL, Karaplis AC, Kovacs CS. Upregulation of calcitriol during pregnancy and skeletal recovery after lactation do not require parathyroid hormone. Journal of Bone and Mineral Research 2013; 28(9): 1987-2000. Epub 17 Mar 2013.

 

65. Kovacs CS. Bone metabolism in the fetus and neonate. Pediatric Nephrology 2014; 29(5):793-803. Epub 26 Mar 2013.

 

66. Langsetmo L, Berger C, Kreiger N, Kovacs CS, Hanley DA, Jamal JA, Whiting SJ, Genest J, Morin SN, Hodsman A, Prior JC, Lentle B, Patel MS, Brown JP, Anastasiades T, Towheed T, Josse RG, Papaioannou A, Adachi JD, Leslie WB, Davison KS, Goltzman D, and the CaMos Group. Calcium and Vitamin D Intake and Mortality: Results from the Canadian Multi-centre Osteoporosis Study (CaMos). Journal of Clinical Endocrinology and Metabolism 2013; 98(7):3010-8. Epub 23 May 2013.

 

67. Kovacs CS, Seshiah V, Swallow R, Jones R, Rattunde H, Woerle HJ and Broedl UC. Empagliflozin improves glycaemic and weight control as add-on therapy to pioglitazone or pioglitazone plus metformin in patients with type 2 diabetes: a 24-week, randomized, placebo-controlled trial. Diabetes, Obesity & Metabolism 2014; 16: 147-158. Epub 1 August 2013.

 

69. Kovacs CS. The role of PTHrP in regulating mineral homeostasis during pregnancy, lactation, and fetal/neonatal development. [invited] Clinical Reviews in Bone and Mineral Metabolism. 2014. Epub 14 Feb 2014.

 

70. Ioannidis G, Pallan S, Papaioannou A, Mulgund M, Rios L, Ma J, Thabane L, Davison KS, Josse RG, Kovacs CS, Kreiger N, Olszynski WP, Prior JC, Towheed T, Adachi JD, and the CaMos Research Group. Glucocorticoids Predict 10-Year Fragility Fracture Risk in a Population-based Ambulatory Cohort of Men and Women: Canadian Multicentre Osteoporosis Study (CaMos). Archives of Osteoporosis 2014; 9(1): 169. Epub 28 Feb 2014.

 

71. Ma Y, Samaraweera M, Cooke-Hubley S, Kirby BJ, Karaplis AC, Lanske BL, Kovacs CS. Neither absence nor excess of FGF23 disturbs murine fetal-placental phosphorus homeostasis or prenatal skeletal development and mineralization. Endocrinology 2014; 155(5):1596-1605. Epub 6 Mar 2014.

 


Partial List of Textbook Chapters

3. Kovacs CS, Kronenberg HM. Skeletal physiology: Pregnancy and lactation. In: Favus MJ (ed), Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 4th ed. Philadelphia: Lippincott, Williams & Wilkins, 1999: 50-4.

5. Kovacs CS. Fetal Mineral Homeostasis. In: Glorieux FH, Pettifor JM, Jüppner H (eds): Pediatric Bone: Biology and Diseases. San Diego: Academic Press, 2003: pp 271-302.

6. Kovacs CS, Kronenberg HM. Skeletal physiology: Pregnancy and lactation. In: Favus MJ (ed), Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 5th ed. Washington, DC: ASBMR Press, 2003: 80-86.

7. Kovacs CS. Skeletal physiology: Fetus and neonate. In: Favus MJ (ed), Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 5th ed. Washington, DC: ASBMR Press, 2003: 65-71.

8. Kovacs CS. Fetal Mineral Homeostasis and Skeletal Mineralization. In: Massaro EJ, Rogers J (eds): The Skeleton: Biochemical, Genetic and Molecular Interactions in Development and Homeostasis. Totowa, NJ: Humana Press, 2004: 293-306.

9. Kovacs CS, Kronenberg HM. Skeletal physiology: Pregnancy and lactation. In: Favus MJ (ed), Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 6th ed. Washington, DC: ASBMR Press, 2006: 63-68.

10. Kovacs CS. Skeletal physiology: Fetus and neonate. In: Favus MJ (ed), Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 6th ed. Washington, DC: ASBMR Press, 2006: 50-55.

11. Kovacs CS. Bone Physiology: Pregnancy and Lactation. In: Teotia SPS (ed): An Asian Perspective on Nutritional and Metabolic Bone and Stone Disease. New Delhi, India: CBS Publishers, 2008: 51-62.

12. Kovacs CS. Bone Physiology: Fetus and Neonate. In: Teotia SPS (ed): An Asian Perspective on Nutritional and Metabolic Bone and Stone Disease. New Delhi, India: CBS Publishers, 2008: 40-50.

13. Wysolmerski JJ, Stewart AF, Kovacs CS. Physiological Actions of Parathyroid Hormone (PTH) and PTH-Related Protein: Epidermal, Mammary, Reproductive, and Pancreatic Tissues. Chapter 29. In: Principles of Bone Biology, 3rd Edition, eds Bilezikian J, Raisz L, Martin TJ, Academic Press, 2008, 713-731.

14. Kovacs CS, Kronenberg HM. Pregnancy and lactation. In: Rosen CJ (ed), Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 7th ed. Washington, DC: ASBMR Press, 2008: 90-95.

15. Kovacs CS. Fetal calcium metabolism. In: Rosen CJ (ed), Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 7th ed. Washington, DC: ASBMR Press, 2008, 108-112.

 

16. Kovacs CS. Calcium metabolism during pregnancy and lactation. In: De Groot, LJ (ed), www.Endotext.com, 2009.

 

17. Kovacs CS.  Fetus and neonate. In: Feldman D, Pike WJ, Adams JS (eds), Vitamin D: Third Edition. New York: Academic Press, 2011, 625-646.

 

18.  Kovacs CS.  Fetal Mineral Homeostasis.  Chapter 11.  In: Glorieux FH, Pettifor JM, Jüppner H (eds): Pediatric Bone: Biology and Diseases, 2nd Edition.  San Diego: Academic Press, 2011: 247-275.

 

19. Kovacs CS. Calcium metabolism during pregnancy and lactation [2nd edition]. In: De Groot, LJ (Ed), www.Endotext.com, 2012.

 

20. Kovacs CS. Fetal control of calcium and phosphate homeostasis – lessons from mouse models. Chapter 14. In: Thakker RV, Whyte MP, Eisman JA, and Igarashi T. Genetics of Bone Biology and Skeletal Disease. San Diego: Academic Press/Elsevier, 2012; p 205-220.

 

21. Kovacs CS. Control of skeletal homeostasis during pregnancy and lactation – lessons from physiological models. Chapter 15. In: Thakker RV, Whyte MP, Eisman JA, and Igarashi T. Genetics of Bone Biology and Skeletal Disease. San Diego: Academic Press/Elsevier, 2012; p 221-240.

 

22. Kovacs CS, Kronenberg HM. Pregnancy and lactation.  In: Rosen CJ (ed), Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 8th ed. Washington, DC: Wiley, 2013: p 156-164.

 

23. Kovacs CS.  Fetal calcium metabolism.  In: Rosen CJ (ed), Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 8th ed. Washington, DC: Wiley, 2013; p 180-187.

 

24. Kovacs CS. Interactions of PTHrP with receptors and signaling. In: Bilezikian JP, Marcus R, Levine M, Marcocci C, Potts J, Silverberg S (eds). The Parathyroids, 3rd Edition. San Diego: Academic Press/Elsevier, 2014: in press.

 

25. Kovacs CS. Parathyroid function and disease during pregnancy, lactation, and fetal/neonatal development. In: Bilezikian JP, Marcus R, Levine M, Marcocci C, Potts J, Silverberg S (eds). The Parathyroids, 3rd Edition. San Diego: Academic Press/Elsevier, 2014: in press.

 

26. Kovacs CS. Hypoparathyroidism during pregnancy, lactation, and fetal/neonatal development. In: Biachi ML, Brown EM (eds). Hypoparathyroidism. Milan: Springer, 2014, in press.

 

Partial List of Books Edited

1. Grubbs DG, Kovacs CS and Crimmins A. Threshold: Volume 1: The Collected Stories of Roger Zelazny. NESFA Press, 2009.

2. Grubbs DG, Kovacs CS and Crimmins A. Power & Light: Volume 2: The Collected Stories of Roger Zelazny. NESFA Press, 2009.

3. Grubbs DG, Kovacs CS and Crimmins A. This Mortal Mountain: Volume 3: The Collected Stories of Roger Zelazny. NESFA Press, 2009.

4. Grubbs DG, Kovacs CS and Crimmins A. Last Exit to Babylon: Volume 4: The Collected Stories of Roger Zelazny. NESFA Press, 2009.

5. Grubbs DG, Kovacs CS and Crimmins A. Nine Black Doves: Volume 5: The Collected Stories of Roger Zelazny. NESFA Press, 2009.

6. Grubbs DG, Kovacs CS and Crimmins A. The Road to Amber: Volume 6: The Collected Stories of Roger Zelazny. NESFA Press, 2009.

7. Fleet JK [author], Kovacs CS [technical editor], Adang V [project editor]. Vitamin D for Dummies. Indianapolis: Wiley Press, 2011.

 

Books Authored

1. Kovacs CS. "And Call Me Roger": The Literary Life of Roger Zelazny. NESFA Press, 2009; published in six parts, one per volume of The Collected Stories of Roger Zelazny.

2. Kovacs CS. The Ides of Octember: A Pictorial Bibliography of Roger Zelazny. NESFA Press, 2010.

3. Ross AC, Abrams SA, Aloia JF, Brannon PM, Clinton SK, Durazo-Arvizu RA, Gallagher JC, Gallo RL, Jones G, Kovacs CS, Manson JE, Mayne ST, Rosen CJ, Shapses SA. Dietary Reference Intakes for Calcium and Vitamin D. Ross AC, Taylor CL, Yaktine AL, Del Valle HB, eds. Washington, DC: Institute of Medicine, 2011. Epub 30 Nov 2010.

4. Kovacs CS. The Ides of Octember: A Pictorial Bibliography of Roger Zelazny. Camelot Books, 2011 [signed, limited, traycased edition]

 
vvv